At IU's Gill Center for Biomolecular Science, a research dream team tackles neuroscience's toughest challenges.
Our Latest Publication Finds a Neuroprotective Role for Caffeine
In our latest publication, a large-scale discovery assay was used to identify factors that increases NMNAT2 levels in the brain. One of those compounds was caffeine, and it has drawn some attention!
Recent Lu Laboratory Publication Reveals Protective Factors Against Neurodegeneration
In the most recent publication from the Lu Laboratory in Scientific Reports, various compounds were screened for their effect on NMNAT2 levels -- a protein we previously identified for its protective role in Alzheimer's disease. Graduate student Gillian Bradley and assistant faculty Dr. Yousuf Ali were the primary contributors to the project with Dr. Hui-Chen Lu.
Lu Laboratory featured on Reddit Science "Ask Me Anything"
On December, 7th, Dr. Hui-Chen Lu, Dr. Yousuf Ali, and Hunter Allen were featured on Reddit as a part of the /r/science "Ask Me Anything" series, where they answered questions from users around the world regarding their recently published work on NMNAT2 in PLoS Biology.
The entire Q&A session can be seen on Reddit and has also been archived permanently for citation at The Winnower (https://doi.org/10.15200/winn.148111.15041).
mGluR5 Exerts Cell-Autonomous Influences on the Functional and Anatomical Development of Layer IV Cortical Neurons in the Mouse Primary Somatosensory Cortex
We've just published a new paper in The Journal of Neuroscience describing the role of mGluR5 in cortical neuron development. Follow the link below to read the full article.
Collaborators Highlighted for PLOS Biology Paper
The American Federation for Aging Research chose to highlight a few of our collaborators, Dr. Giulio Taglialatela and Dr. Joshua Shulman, for their contributions to our most recent publication in PLOS Biology.
More Press Following PLOS Biology Publication
Many press releases, in a number of different languages and countries, have followed the publication of our latest paper in PLOS Biology. Below you can find links to a few of the articles.
PLOS Biology Article Generating Attention
Our latest publication in PLOS Biology, NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies, has generated a lot of attention among the scientific and medical communities.
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies
We have just published a new paper, now in press in PLOS Biology, focusing on NMNAT2's role as a molecular chaperone and neuronal maintenance factor in the context of Alzheimer's disease and other proteinopathies.